- In H20 is 0.17 mM (0.009%).
- In 0.2M NaCl decreases to 0.12mM (0.006%).
If you need further information on how either of the two concentrations listed above were obtained, you can find the studies here. For Water and for the Sodium Chloride Solution you should search, Professor R. M. Garavito our visit his page at Michigan State University. You may need to contact Dr. Garavito to learn more about his studies.
Importance of CMC of Dodecyl Maltoside and other Detergents?
CMC or Critical Micelle Concentration is a quantitative measure used to define the behavior of a surfactant (protein detergents) in solution and varies for each detergent. It provides information on the concentration required for the formation of micelles.
Of course depending on exactly what is being studied, knowing this information for a specific detergent can be useful to chemists, protein biologists and physicists alike. It gives insight into the behavior of the detergent and serves as a quantitative measure helping the the scientist choose the most appropriate detergent to include in their study and also helps in setting up the protocol in their future experiments.
Detergents interact with proteins and/or the cell membrane in the form of self-assembled aggregates defined as micelles. The CMC is the concentration of the specific detergent (surfactant) required for the formation of micelles, typically measured in a water or salt solution.
Micellization or the formation of Micelles.
Important to understand - the range of micelle formation is tight.
The CMC of dodecyl maltoside in water is 0.17 mM at this point micelles will form but once this it becomes greater than 0.17 what occurs. Explained in the following summary:
At low concentrations (below CMC) detergents exist as monomers in solution. As more detergent is added and the concentration reaches the CMC, micelles form.
If more detergent is added above 0.17 mM for dodecyl maltoside then monomers will again begin to exist. These monomers will exist at the concentration equal to CMC and micelles will exist at total detergent concentration - CMC.
Other important factors to take into consideration:
CMC or Critical Micelle Concentration is a quantitative measure used to define the behavior of a surfactant (protein detergents) in solution and varies for each detergent. It provides information on the concentration required for the formation of micelles.
Of course depending on exactly what is being studied, knowing this information for a specific detergent can be useful to chemists, protein biologists and physicists alike. It gives insight into the behavior of the detergent and serves as a quantitative measure helping the the scientist choose the most appropriate detergent to include in their study and also helps in setting up the protocol in their future experiments.
Detergents interact with proteins and/or the cell membrane in the form of self-assembled aggregates defined as micelles. The CMC is the concentration of the specific detergent (surfactant) required for the formation of micelles, typically measured in a water or salt solution.
Micellization or the formation of Micelles.
Important to understand - the range of micelle formation is tight.
The CMC of dodecyl maltoside in water is 0.17 mM at this point micelles will form but once this it becomes greater than 0.17 what occurs. Explained in the following summary:
At low concentrations (below CMC) detergents exist as monomers in solution. As more detergent is added and the concentration reaches the CMC, micelles form.
If more detergent is added above 0.17 mM for dodecyl maltoside then monomers will again begin to exist. These monomers will exist at the concentration equal to CMC and micelles will exist at total detergent concentration - CMC.
Other important factors to take into consideration:
- Effects of Hyodrophilic groups
- Effects of Hydrophobic groups
- Effects of Electrolytes
If you would like to learn more about dodecyl maltoside start at our homepage
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